Detalhe da pesquisa
1.
Structure of a B12-dependent radical SAM enzyme in carbapenem biosynthesis.
Nature
; 602(7896): 343-348, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35110734
2.
ThnL, a B12-dependent radical S-adenosylmethionine enzyme, catalyzes thioether bond formation in carbapenem biosynthesis.
Proc Natl Acad Sci U S A
; 119(34): e2206494119, 2022 08 23.
Artigo
Inglês
| MEDLINE | ID: mdl-35969793
3.
SAR of non-hydrolysable analogs of pyridoxal 5'-phosphate against low molecular weight protein tyrosine phosphatase isoforms.
Bioorg Med Chem Lett
; 30(16): 127342, 2020 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32631543
4.
Stereochemical course of cobalamin-dependent radical SAM methylation by TokK and ThnK.
RSC Chem Biol
; 3(8): 1028-1034, 2022 Aug 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36042702
5.
Evolution of Methods for the Study of Cobalamin-Dependent Radical SAM Enzymes.
ACS Bio Med Chem Au
; 2(1): 4-10, 2022 Feb 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35341020
6.
Purification and characterization of sequential cobalamin-dependent radical SAM methylases ThnK and TokK in carbapenem ß-lactam antibiotic biosynthesis.
Methods Enzymol
; 669: 29-44, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35644176
7.
Methylations in complex carbapenem biosynthesis are catalyzed by a single cobalamin-dependent radical S-adenosylmethionine enzyme.
Chem Commun (Camb)
; 55(99): 14934-14937, 2019 Dec 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31774078